The instrument is intended as a screening platform for protein design and an instrument for protein characterization more broadly. To work in protein design context, it needs to work in a crudely purified (ideally unpurified) context and with minimal samples typically less than 1 g. This requires measurement at 640nm and built-in-in viscosity compensation. Additionally, it needs to work without extrinsic labelling requiring measurement at 280 nm. Measurement at 480 nm is required compatibility with a range of other instruments in our lab.
The FIDA instrument is uniquely able to fulfill the above requirement and there are currently no other techniques combining all these features into a single instrument.
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